業績リスト

2022.06.06

原著論文（2000年以降）

  • A. Ishii, T. Hata, Y. Shigeta, and H. Urabe, “Nucleophilic Addition of Amides to Haloalkynes: Synthesis of (Z)-β-Halovinylamides as Dual Precursors of Allyl Halides and Alkylidene Carbenes.” Org. Lett., in press (2024).
  • T. Hata, Y. Tatsumi, Y. Kanai, N. Takahashi, M. Shigeta, and H. Urabe, “Preparation of Hetero-π-conjugated Compounds by Double Nucleophilic Addition to Haloalkynes and C-H Cyclization.” Adv. Synth. Catal., in press (2024).
  • T. Abe, K. Kobayashi, S. Kikukawa, Y. Kanai, and T. Hata, “Rhodium-Catalyzed Intramolecular Cyclization and Rearrangement of 1-Azido-2-(2,2-Dihalovinyl)arenes and 1-Azido-2-[(2,2-Dihalovinyl)(Boc)amino]arenes for the Preparation of 2,3-Dihaloindoles and 2-Haloquinoxalines.” Adv. Synth. Catal., 365, 4562-4566 (2023).
  • K. Kobayashi, N. Kasakura, S. Kikukawa, S. Matsumoto, S. Karasawa, and T. Hata, “Facile Preparation of Polycyclic Halogen-substituted 1,2,3-Triazoles by Using Intramolecular Huisgen Cycloaddition.” Org. Biomol. Chem., 21, 9610-9615 (2023).
  • K. Miyanaka, T. Harada, M. Shigeta, T. Hata, and H. Urabe, “Iron-catalyzed Regio- and Stereoselective Substitution of 2,4-Alkadienyl Carboxylates with Aryl Grignard Reagents.” Tetrahedron Lett., 133, 154824 (2023).
  • T. Hata, Y. Hayashi, Y. Hasegawa, M. Iwai, A. Ishii, M. Hasegawa, M. Shigeta, and H. Urabe, “Preparation of Tetrazole-fused π-Conjugated Molecules and Their Fluorescence Behavior,” Chem. Lett., 48, 662-665 (2019).
  • G. Sugano, K. Kawada, M. Shigeta, T. Hata, and H. Urabe, “Iron-catalyzed δ-Selective Conjugate Addition of Methyl and Cyclopropyl Grignard Reagents to α,β,γ,δ-Unsaturated Carbonyl Compounds,” Tetrahedron Lett., 60, 885-890 (2019).
  • A. Furukawa, T. Hata, M. Shigeta, and H. Urabe, “Rh-catalyzed Intramolecular Cyclization of N-Sulfonyltriazole and Sulfinate. Concise Preparation of Sulfonylated Unsaturated Piperidines,” Tetrahedron Lett., 60, 815-819 (2019).
  • M. Senoo, A. Furukawa, T. Hata, and H. Urabe, “Rh-catalyzed Intramolecular C-H Bond Activation with Triazoles. Preparation of Stereo-defined Pyrrolidines and Other Related Cyclic Compounds,” Chem. Eur. J., 22, 890-895 (2016).
  • M. Yamagishi, A. Ishii, T. Hata, and H. Urabe, “Facile Preparation of 1,2-Dihydroisoquinolines from N-Benzylsulfonamides and Bromoacetylenes,” Heterocycles, 90, 847-856 (2015). (Current Special Issue: Isao Kuwajima’s Special Issues)
  • T. Mizumori, T. Hata, and H. Urabe, “Alkylation of Pyridines at Their 4-Position with Stylenes plus an Yttrium Reagent or Benzyl Grignard Reagents,” Chem. Eur. J., 21, 422-426 (2015).
  • H. Murase, K. Senda, M. Senoo, T. Hata, and H. Urabe, “Rhodium-catalyzed Intramolecular Hydroarylation of 1-Halo-1-alkynes. Regioselective Synthesis of Semihydrogenated Aromatic Heterocycles,” Chem. Eur. J., 20, 317-322 (2014).
  • T. Hata, H. Gotoh, T. Yokomizo, and H. Urabe, “Iron-catalyzed 1,6-Selective Addition of Aryl Grignard Reagent to tert-Butyl (Z)-5-Phenyl-3-hexenoate,” Org. Synth., 91, 307-321 (2014).
  • T. Hata, T. Nakada, O. Y. Taek, N. Hirone, and H. Urabe, “Iron-Catalyzed Regio- and Stereoselective Conjugate Addition of Aryl Grignard Reagents to α,β,γ,δ-Unsaturated Sulfones and Its Synthetic Application,” Adv. Synth. Catal., 355, 1736-1740 (2013).
  • S. Iwata, M. Senoo, T. Hata, and H. Urabe, “Preparation of S-Aryl Arenethiosulfonates from N,N-Di(arenesulfonyl)hydrazines. Reduction of Sulfonyl Chlorides with an Organic Reagent,” Heteroat. Chem., 24, 336-344 (2013).
  • M. Yamagishi, K. Nishigai, A. Ishii, T. Hata, and H. Urabe, “Facile Preparation of Indoles and 1,2-Benzothiazine 1,1-Dioxides via Nucleophilic Addition of Sulfonamides to Bromoacetylenes Followed by Pd-Catalyzed Cyclization,” Angew. Chem. Int. Ed., 51, 6471-6474 (2012).
  • T. Hata, H. Imade, and H. Urabe, “Four Nucleophilic Additions to Alkenynedioic Acid Derivatives in Tandem; Efficient One-pot Synthesis of Bicyclo[4.2.0]octenols,” Org. Lett., 14, 2450-2453 (2012).
  • M. Yamagishi, K. Nishigai, A. Ishii, T. Hata, and H. Urabe, “Nucleophilic Addition of Sulfonamides to Bromoacetylenes: Facile Preparation of Pyrroles,” Org. Lett., 14, 34-37 (2012).
  • T. Hata, S. Iwata, S. Seto, and H. Urabe, “Iron-Catalyzed Synthesis of Allenes from 2-Alken-4-ynoates and Grignard Reagents” Adv. Synth. Catal. 354, 1885-1889 (2012).
  • T. Hata, S. Sujaku, N. Hirone, K. Nakano, J. Imoto, H. Imade, and H. Urabe, “Iron-Mediated and -Catalyzed Metallative Cyclization of Electron Withdrawing Group-substituted Alkynes and Alkenes with Grignard Reagents,” Chem.-Eur. J., 17, 14593-14602 (2011).
  • Y. T. Oh, K. Senda, T. Hata, and H. Urabe, “Rh-catalyzed Intramolecular Debenzylative Cyclization of Amines. Butyrolactams from Benzylamines Having a Chloroacetylene Moiety,” Tetrahedron Lett., 52, 2458-2461 (2011).
  • N. Hirone, H. Sanjiki, R. Tanaka, T. Hata, and H. Urabe, “Acceleration of the Substitution of Silanes with Grignard Reagents by Using either LiCl or YCl3/MeLi,” Angew. Chem. Int. Ed., 49, 7762-7764 (2010).
  • Y. Kato, D. H. Yen, T. Hata, and H. Urabe, “Aryl(sulfonyl)amino Group: A Convenient and Stable yet Activated Modification of Amino Group for Its Intramolecular Displacement,” Org. Lett., 12, 4137-4139 (2010).
  • H. Naito, T. Hata, and H. Urabe, “Selective Deprotection of Methanesulfonamides to Amines,” Org. Lett., 12, 1228-1231 (2010).
  • T. Hata, R. Bannai, M. Otsuki, and H. Urabe, “Iron-Catalyzed Regio- and Stereoselective Substitution of γ,δ-Epoxy-α,β-unsaturated Esters and Amides with Grignard Reagents,” Org. Lett., 12, 1012-1014 (2010).
  • D. Shikanai, H. Murase, T. Hata, and H. Urabe, “Rh-catalyzed Isomerization and Intramolecular Redox Reaction of Alkynyl Ethers Affording Dihydropyrans and Ketoolefins,” J. Am. Chem. Soc., 131, 3166-3167 (2009).
  • S. Okada,† K. Arayama,† R. Murayama, T. Ishizuka, K. Hara, N. Hirone, T. Hata, and H. Urabe, “Iron-Catalyst-Switched Selective Conjugate Addition of Grignard Reagents. α,β,γ,δ-Unsaturated Amides as Versatile Templates for Asymmetric Three-Component Coupling Process,” Angew. Chem. Int. Ed., 47, 6860-6864 (2008). † Equal contribution
  • R. Tanaka, H. Sanjiki, and H. Urabe, “Yttrium-Mediated Conversion of Vinyl Grignard Reagent to a 1,2-Dimetalated Ethane and Its Synthetic Application,” J. Am. Chem. Soc., 130, 2904-2905 (2008).
  • Y. Fukudome, H. Naito, T. Hata, and H. Urabe, “Copper-Catalyzed 1,2-Double Amination of 1-Halo-1-alkynes. Concise Synthesis of Protected Tetrahydropyrazines and Related Heterocyclic Compounds,” J. Am. Chem. Soc., 130, 1820-1821 (2008).
  • H. Naito, T. Hata, and H. Urabe, “Facile Preparation of N-Protected 2-Alkylidene-1,3-imidazolidines,” Tetrahedron Lett., 49, 2298-3201 (2008).
  • H. Urabe, D. Shikanai, K. Arayama, T. Sato, and R. Tanaka, ” Electrophile-triggered Assembly of Metal Enamides and Allyl Grignard Reagent in One Pot. Novel Nucleophilic Double Allylation of Azadienes,” Chem. Lett., 36, 556-557 (2007).
  • S. Hirano, Y. Fukudome, R. Tanaka, F. Sato, and H. Urabe, “Practical Preparation of N-(1-Alkynyl)sulfonamides and Their Synthetic Utility in Titanium Alkoxide-Mediated Coupling Reactions,” Tetrahedron (Symposium-in-Print), 62, 3896-3916 (2006).
  • Y. Nobe, K. Arayama, and H. Urabe, “Air-Assisted Addition of Grignard Reagents to Olefins. A Simple Protocol for Three-Component Coupling Process Yielding Alcohols,” J. Am. Chem. Soc., 127, 18006-18007 (2005).
  • R. Tanaka, A. Yuza, Y. Watai, D. Suzuki, Y. Takayama, F. Sato, and H. Urabe, “One-Pot Synthesis of Metalated Pyridines from Two Acetylenes, a Nitrile, and a Titanium(II) Alkoxide,” J. Am. Chem. Soc., 127, 7774-7780 (2005).
  • D. Suzuki, Y. Nobe, Y. Watai, R. Tanaka, Y. Takayama, F. Sato, and H. Urabe, “Facile Preparation of Various Heteroaromatic Compounds via Azatitanacyclopentadiene Intermediates,” J. Am. Chem. Soc., 127, 7474-7479 (2005).
  • K. Fukuhara and H. Urabe, “Iron-Catalyzed 1,6-Addition of Aryl Grignard Reagents to 2,4-Dienoates and -Dienamides,” Tetrahedron Lett., 46, 603-606 (2005).
  • R. Tanaka, M. Sasaki, F. Sato, and H. Urabe, “A Novel Propargyltitanation of Acetylenes. Heteroatom Substituent-Dependent Manifold in Intermolecular Coupling of Allene and Acetylene,” Tetrahedron Lett., 46, 329-332 (2005).
  • S. Hirano, R. Tanaka, H. Urabe, and F. Sato, “Practical Preparation of N-(1-Alkynyl)sulfonamides and Their Remote Diastereoselective Addition to Aldehydes via Titanation,” Org. Lett., 6, 727-729 (2004).
  • K. Mitsui, T. Sato, H. Urabe, and F. Sato, “Stereoselective Construction of Acyclic Carbon Chains via One-pot Coupling Process Based on Alkenyloxazoline-Titanium Complexes,” Angew. Chem. Int. Ed., 43, 490-492 (2004).
  • H. Urabe, K. Mitsui, S. Ohta, and F. Sato, “Titanium Alkoxide Complex of Functionalized Conjugated Dienes. A Versatile Bis-anionic Template for Stereoselective Construction of Carbon Frameworks,” J. Am. Chem. Soc., 125, 6074-6075 (2003).
  • H. Urabe, D. Suzuki, M. Sasaki, and F. Sato, “Enol Ester as an Olefinic Partner in Enyne Cyclization. A Novel Tandem Cyclization to Stereo-defined Bicyclo[3.3.0]octenes,” J. Am. Chem. Soc., 125, 4036-4037 (2003).
  • H. Urabe, D. Suzuki, and F. Sato, “Generation of an Acetylene-titanium Alkoxide Complex. Preparation of (Z)-1,2-Dideuterio-1-(trimethylsilyl)-1-hexene,” Org. Synth., 80, 120-128 (2003).
  • R. Tanaka, S. Hirano, H. Urabe, and F. Sato, “Concise and Stereoselective Synthesis of Enamides and Dienamides by Titanium-Mediated Coupling Method,” Org. Lett., 5, 67-70 (2003).
  • R. Tanaka, Y. Nakano, D. Suzuki, H. Urabe, and F. Sato, “Selective Preparation of Benzyltitanium Compounds by the Metalative Reppe Reaction. Its Application to the First Synthesis of Alcyopterosin A,” J. Am. Chem. Soc., 124, 9682-9683 (2002).
  • M. Narita, H. Urabe, and F. Sato, “Sulfur-Functionalized Olefins for Titanacycle Formation: Tandem Asymmetric Cyclization and the Pummerer Reaction Based on Sulfoxides Promoted by Titanium(II)-to-Titanium(IV) Relay,” Angew. Chem. Int. Ed., 41, 3671-3674 (2002).
  • D. Suzuki, R. Tanaka, H. Urabe, and F. Sato, “Selective Syntheses of Metalated Pyridines from Two Different Unsymmetrical Acetylenes, a Nitrile, and a Titanium(II) Alkoxide,” J. Am. Chem. Soc., 124, 3518-3519 (2002).
  • C. Delas, H. Urabe, and F. Sato, “Stereoselective One-pot Preparation of 1,2,4,5-Tetraalkylidene- and 1,4-Dialkylidenecyclohexanes,” Chem. Commun., 820-821 (2002).
  • C. Delas, H. Urabe, and F. Sato, “Site-selective Mono-titanation of Conjugated Diynes with a Ti(II) Alkoxide Reagent. Concise Preparation of Stereo-Defined Enynes and Dienynes,” Chem. Commun., 272-273 (2002).
  • H. Urabe, K. Kusaka, D. Suzuki, and F. Sato, “Chiral 1,3-Butadiene-2-carboxylates for an Efficient Asymmetric Diels-Alder Reaction,” Tetrahedron Lett., 43, 285-289 (2002).
  • R. Nakajima, H. Urabe, and F. Sato, “Intramolecular Coupling of Vinyl Ether and Olefins or Acetylenes with Ti(II) Reagent. Regio- and Stereoselective Vinyltitanation of Carbon-Carbon Multiple Bonds,” Chem. Lett., 4-5 (2002).
  • C. Delas, H. Urabe, and F. Sato, “Remarkably Facile, Unidirectional Isomerization of Titanated Vinylallenes to Cyclobutenyltitanium Compounds. A Practical Construction of a Cyclobutene Framework,” J. Am. Chem. Soc., 123, 7937-7938 (2001).
  • D. Suzuki, H. Urabe, and F. Sato, “Metalative Reppe Reaction. Organized Assembly of Acetylene Molecules on Titanium Template Leading to a New Style of Acetylene Cyclotrimerization,” J. Am. Chem. Soc., 123, 7925-7926 (2001).
  • C. Delas, H. Urabe, and F. Sato, “Titanium-Mediated Intramolecular Cyclization of Tethered Propargyl Alcohol Derivatives. Access to Exocyclic Bis-Allenes and Cyclobutene Derivatives,” Tetrahedron Lett., 42, 4147-4150 (2001).
  • H. Urabe, R. Nakajima, and F. Sato, “A Facile Preparation of exo-Cyclic Conjugated Dienes Fused to Lactams or Lactones via Intramolecular Coupling of Acetylenes and Their Behavior in Diels-Alder Reactions,” Org. Lett., 2, 3481-3484 (2000).
  • R. Mizojiri, H. Urabe, and F. Sato, “Generation of a Silylethylene-Titanium Alkoxide Complex. A Versatile Reagent for Silylethylation and Silylethylidenation of Unsaturated Compounds,” J. Org. Chem., 65, 6217-6222 (2000).
  • D. Suzuki, H. Urabe, and F. Sato, “Asymmetric Synthesis of Baylis-Hillman-Type Allyl Alcohols via a Chiral Acetylenic Ester-Titanium Alkoxide Complex,” Angew. Chem. Int. Ed., 39, 3290-3292 (2000).
  • T. Hamada, R. Mizojiri, H. Urabe, and F. Sato, “Expedient Construction of Multiple Stereogenic Centers in an Acyclic System via the Addition of Aldehydes, Ketones, and Chiral Imines to an Enyne-Titanium Alkoxide Complex,” J. Am. Chem. Soc., 122, 7138-7139 (2000).
  • H. Urabe, D. Hideura, and F. Sato, “Asymmetric Synthesis of Bicyclic Ketones Having an Angular Substituent via Ti(II) Alkoxide-Mediated Tandem Cyclization of Tri-substituted Olefinic Substrates,” Org. Lett., 2, 381-383 (2000).

総説等（2000年以降）

  • T. Hata, “Synthetic Methods Using Interaction Between Sustainable Iron Reagent and Functionalized Carbon-Carbon Multiple Bonds,” in Molecular Technology, (Volume 4: Synthesis Innovation) Yamamoto, H, Kato, T, Eds., Wiley-VCH, pp. 51-76 (2019).
  • 秦、”鉄試薬による官能性炭素−炭素多重結合の制御を利用する新規合成手法の開発”、有機合成化学協会誌、72, 972-982 (2014).
  • 占部、秦、”第4章 芳香族化合物 – 医薬品化学への展開”、生命理工系のための大学院基礎講座 – 有機化学、湯浅英哉・編、東京工業大学出版会・工学図書、pp. 67-90 (2011).
  • H. Urabe and F. Sato, “Titanocene (Cp2Ti(II)” in Encyclopedia of Reagents for Organic Synthesis, 2nd ed.; L. A. Paquette, D. Crich, P. L. Fuchs, G. A. Molander, Eds., Wiley: Chichester, Vol. 12, pp. 9590-9595 (2009).
  • 占部、秦、”バイオ研究のフロンティア　医療・診断をめざす先端バイオテクノロジー3、（13章 医薬・生体機能分子の未来指向型合成法の開発）”関根光雄・編、東京工業大学出版会・工学図書、pp. 118-130 (2009).
  • 占部、”バイオ系のための基礎化学問題集”、’第10章 アルケン・アルキン/第11章 官能基変換’、講談社サイエンティフィク, pp. 132-143 (2008).
  • 占部、”メタラサイクルをテンプレートとする多成分連結反応の開発”、化学工業、57, 757-762 (2006).
  • 占部、”4族(Ti,Zr)メタラサイクルを経るヘテロ環化合物の合成法－アセチレン、オレフィン、およびヘテロ不飽和化合物の環化反応”、有機合成化学協会誌、63, 102-111 (2005).
  • 西山、石原、村上、占部、中村、柴田、八谷、”２０年後に有機合成はどこに行くのか”、有機合成化学協会誌、62, 933-938 (2004).
  • H. Urabe and F. Sato, “Titanocene (Cp2Ti(II)” in Electronic Encyclopedia of Reagents for Organic Synthesis, L. A. Paquette, Ed., Wiley: Chichester (2003).
  • H. Urabe, “New Synthetic Reactions Mediated by Organometallic Compounds” in My Favorite Organic Synthesis, 有機合成化学協会・竜田邦明・福山透編、化学同人、pp. 244-245 (2002).
  • F. Sato and H. Urabe, “Chapter 9. Titanium(II) Alkoxide in Organic Synthesis” in Titanium and Zirconium in Organic Synthesis, I. Marek, Ed., Wiley-VCH: Weinheim, pp. 319-354 (2002).
  • 占部、”チタナサイクルによる有機合成の新しい幕開け”、有機合成化学協会誌、59, 438-439 (2001).
  • F. Sato, H. Urabe, and S. Okamoto, “Synthesis of Organotitanium Complexes from Alkenes and Alkynes, and Their Synthetic Application,” Chem. Rev., 100, 2835-2886 (2000).
  • F. Sato, H. Urabe, and S. Okamoto, “Synthetic Reactions Mediated by a Ti(O-i-Pr)4 / 2 i-PrMgX Reagent,” Synlett, 753-775 (2000).
  • F. Sato and H. Urabe, “Chapter 3. Hydromagnesiation of Alkenes and Alkynes” in Grignard Reagents – New Developments, H. G. Richey, Jr., Ed., Wiley: Chichester, pp. 65-105 (2000).
  • H. Urabe and F. Sato, “Chapter 15. Titanium(IV) Lewis Acids” in Lewis Acids in Organic Synthesis, H. Yamamoto, Ed., Wiley-VCH: Weinheim, Vol. 2, pp. 653-798 (2000).
  • 占部、”共役ジ－、テトラ－、およびヘキサイン－チタン錯体の構造と反応”、Organometallic News, 55 (2000).
  • 占部、”有機合成における華やかな金属試薬・チタン”、ファルマシア、36, 612-613 (2000).